I’m a DNA polymerase. I need a primer to bond with others, to start a conversation, and to fix my mistakes. My life is broken and going backwards. I’m full of Okazaki fragments. I’m a globular protein. I’m free-floating, trying to fold into a […]
Category: SCIENCE
Another crack at the FTO locus and a cautionary note on gene knock-out
This paper from the Kellis lab is a great demostration of how functional genomic studies should be in the post hight throughput sequencing era. They took on a classic GWAS example, obesity, which has a fairly high genetic component, up to 80% heritability. A 47kb region […]
HHMI meeting Day 3
Today was all systems neuroscience, an area that I don’t quite get. And because of this lack of understanding, research in this field usually falls into two categories to me: questions too simple to study, and questions too lofty to grasp. But still, I […]
HHMI meeting Day 2
It was a busy day packed with all sorts of exciting science and personality. Totally didn’t sleep well last night. Luckily the meeting started with works from Kolodkin and Engle labs that I’m quite familiar with. So that was a easy wake up transition […]
HHMI meeting Day 1
It’s been a while since my last post about science. Today is the first evening of the three day Howard Hughes meeting at Janelia. I’m here for the science and I’m on a mission of a first look at my next project in a […]